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Abstract #2757

Analysis of  T2 and T2* relaxation time reproducibility within hip joint cartilage

Jessica Bugeja1,2, Ales Neubert1,2, Shekhar Chandra1, Jurgen Fripp2, Craig Engstrom1, and Stuart Crozier1
1University of Queensland, Brisbane, Australia, 2CSIRO, Brisbane, Australia

QMRI sequences including T2 and T2* mapping analyse biochemical changes of cartilage including the deterioration of the ECM and changes in water content for early diagnosis of hip OA prior to serious cartilage degradation. Longitudinal studies and clinical assessments with T2 and T2* mapping rely on a high reproducibility of the tissue relaxation times for accurate diagnosis. We present a statistical analysis of the reproducibility of T2 and T2* mapping of hip MR images. An automated cartilage segmentation method is used for the segmentation of FISP MR hip images and biochemical information is obtained from the T2 and T2* images.

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