We quantitatively evaluate the microvascular permeability of lumbar marrow changes in alloxan-induced diabetic rabbits using dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) . And to investigate whether texture analysis based on permeability parameter Ktrans map of DCE-MRI can be used to assess the fine alterations of lumbar marrow structures in early-stage diabetic rabbits.
Our results confirm that texture analysis parameters based on DCE-MRI quantitative parameter Ktrans map are feasible to identify the early-stage fine changes of lumbar marrow structure in diabetic rabbits.
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