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Abstract #2775

Quantitative Magnetization Transfer Imaging of the Lumbar in Primary Osteoporosis at 3T MRI: a Feasibility Study

Fan Qiuju1, Tan Hui1, Yang Zhen1, Yu Nan1, Yu Yong1, Wang Shaoyu2, Xue Yu3, and Li Yue3
1Affiliated Hospital of Shaanxi University of Chinese Medicine, Shaanxi, China, 2MR senior scientific marketing specialist, Shaanxi, China, 3Shaanxi University of Chinese Medicine, Shaanxi, China

This study aimed to assess the association between the magnetization transfer ratio (MTR) value and bone mineral density (BMD) in lumbar vertebral among normal, osteopenia and osteoporosis. The MT technique was used to evaluate 26 healthy volunteers, 26 osteopenia patients and 24 osteoporosis patients. The MTR in the osteoporotic, osteopenic, and normal BMD groups were statistically significant differences. Therefore, MT technique provide quantitative information about the contribution of macromolecules., which can be used as a non-invasive quantitative monitoring MRI tool for osteoporosis progression.

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