Meeting Banner
Abstract #2813

Stirring STIR contrast

Nick Zafeiropoulos1, Stephen Wastling1, Jasper Morrow2, Uros Klickovic1, Pietro Fratta1, Sachet Shah1, Enrico De Vita3, Mary M Reilly2, Tarek Yousry1, and John Thornton1
1UCL Queen Square Institute of Neurology, London, United Kingdom, 2MRC Centre for Neuromuscular Diseases, London, United Kingdom, 3King's College London, London, United Kingdom

In vivo lower-limb STIR images were compared with images simulated using a theoretical signal model with experimentally determined muscle-water T2 and fat fraction values. Nominally T2-weighted STIR contrast is seen to depend on changing tissue-water relative proton density as fat content increases in diseased muscle, in addition to expected T2 dependent changes. Imperfect inversion-recovery fat nulling may also cause unexpected hyper-intensity in regions of high fat content. These observations may have implications for the clinical interpretation of STIR signal intensity.

This abstract and the presentation materials are available to members only; a login is required.

Join Here