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Abstract #2822

Histogram analysis of T2* value for lumbar intervertebral disc degeneration

Xiaoqing Liang1, Ruyi Xie1, Yitong Li1, Bowen Hou1, Weiyin Vivian Liu2, and Xiaoming Li1
1Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 2MR Research,GE Healthcare, Beijing, China

Low back pain (LBP) is a common spinal disease during the middle-to-old-aged population. Degeneration of lumbar intervertebral discs (IVDs) is recognized as the common and crucial cause of LBP. Histogram analysis is a recently popular method for assessing microstructural heterogeneity, however, its diagnostic performance in intervertebral disc degeneration hasn’t been proved. Histogram analysis on axial T2* mapping was applied to characterize degenerative degrees and heterogeneity of discs. All histogram parameters of T2* value were significantly related to Pfirrmann grading. Our study confirmed that the apparent “red zone” on T2* color maps was clearly related to degeneration.

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