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Abstract #2823

Diffusion kurtosis imaging and  intravoxel incoherent motion in quantitative evalutation of lumbar intervertebral disc degeneration

Feifei Zeng1, Yunfei Zha2, and Weiyin Liu3
1Radiology, Renmin Hospital of Wuhan University, Wuhan, China, 2Renmin Hospital of Wuhan University, Wuhan, China, 3MR Research, GE Healthcare, Bejing, China

The purpose of this study is to compare the diagnostic value of diffusion kurtosis imaging (DKI) and intravoxel incoherent motion(IVIM) in assessing lumbar intervertebral disc degeneration. DKI parameters ( MK, MD, and FA), and IVIM parameters (ADCstandard, ADCslow, ADCfast, and f) of nucleus pulposus (NP), anterior annulus fibrosus (AAF) and posterior annulus fibrosus (PAF) were measured and correlated with Pfirrmann grades. It was found that DKI and IVIM parameters had significantly correlation with Pfirrmann grades. In addition, DKI was more sensitive than IVIM in quantitative detection of early lumbar intervertebral disc degeneration.

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