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Abstract #2832

Study on the optimization of BOLD magnetic resonance ischemia-reactive hyperemia model of skeletal muscle of calf

Chunye Geng1 and Jianling Cui1
1The Third Hospital of Hebei Medical University, Shijiazhuang, China

In BOLD-MRI studies, cuff compression was often used to establish the ischemia-reactive hyperemia model of calf muscle.We found some BOLD signals did not decrease during ischemia, but increased or stay the same.This study was to find the reasons why BOLD signal showed multiple trends in ischemic period and to optimize the ischemia model. BOLD scan was performed on volunteers under two cuff pressures.BOLD signals of all muscles showed a downward trend in the P1 model of partly reduced blood supply. However, in P2 model of blood supply blocked completely, BOLD signals had mostly gone up during ischemia ,unexpectedly.

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