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Abstract #2866

Metabolite-cycled echo-planar spectroscopic imaging of the human heart

Sophie M. Peereboom1 and Sebastian Kozerke1
1Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland

Cardiac triglyceride levels can be assessed using proton MR spectroscopy. While metabolite cycling has already been applied to cardiac proton MRS, the combination of metabolite cycling and spectroscopic imaging for cardiac applications remains to be demonstrated. In this work metabolite-cycled echo-planar spectroscopic imaging is proposed to asses triglyceride-to-water (TG/W) ratios in different regions of the human heart. Results were compared to conventional single-voxel measurements in the interventricular septum. Although SNR is limited for metabolite-cycled EPSI, the method allows for detection of regional TG/W and therefore holds promise to provide insights into regional TG variations.

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