Signal combination algorithms, designed for 1D MRS, were adapted for lipid composition spectra acquired using 2D MRS of double quantum filtered correlation spectroscopy (DQF-COSY). The algorithms of adaptively optimised combination (AOC), noise decorrelated combination (nd-comb), and whitened singular value decomposition (WSVD) were evaluated on lipid composition spectra from healthy volunteers and patients with breast cancer (tumour and peritumoural adipose tissue). WSVD provided maximal SNR uniformly across all spectral peaks. WSVD, through the elimination of additional acquired reference spectrum, shortens acquisition in patients to less than 11 min instead of 17 min while maintaining sensitivity.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords