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Abstract #2877

Targeted fast spectroscopic imaging at 7T

Jullie W Pan1, Victor Yushmanov1, Chan H Moon1, Frank Lieberman2, and Hoby P Hetherington1
1Radiology, University of Pittsburgh, Pittsburgh, PA, United States, 2Neurology, UPMC, Pittsburgh, PA, United States

The increased SNR at 7T and high efficiency of spatial encoding from fast readout trajectories means that substantially accelerated spectroscopic imaging acquisitions are practical. In this report, we implement targeted multi-slice Hadamard encoded cascaded and simultaneous acquisitions. With the cascaded rosette, minimal CSDE is incurred, generating 4slices in 8min12s. The J-refocused sequence achieves excellent CRLB in <2.3min for a single slice. With a B1 reduction strategy that allows multiple simultaneous Hadamard encoding, the J-refocused sequence is also demonstrated with 4slice acquisitions. As performed in brain tumor patients, the targeted Hadamard rosette is well tolerated and sensitive for detection of pathology.

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