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Abstract #2880

The impact of receiver bandwidth and number of points on MRS fitting accuracy

Maria Yanez Lopez1 and Peter J Lally2
1Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, United Kingdom

The aim of this work was to investigate the effect of receiver bandwidth and number of points in the fitting of MRS spectra acquired in healthy controls, using a LASER MRS sequence at 3T. Our results highlight the need for harmonisation between different studies in terms of BW/number of points wherever possible, since variations across clinical populations might not be detected due to systematic errors induced from variations in these parameters alone. Optimisation of BW/number of points is also encouraged when setting up a new study.

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