The aim of this work was to investigate the effect of receiver bandwidth and number of points in the fitting of MRS spectra acquired in healthy controls, using a LASER MRS sequence at 3T. Our results highlight the need for harmonisation between different studies in terms of BW/number of points wherever possible, since variations across clinical populations might not be detected due to systematic errors induced from variations in these parameters alone. Optimisation of BW/number of points is also encouraged when setting up a new study.
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