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Abstract #2888

Proton NMR metabolomics guided prediction of anti-obesity properties of medicinal plants

Rama Jayasundar1, Aruna Singh1, and Dushyant Kumar1
1Department of NMR, All India Institute of Medical Sciences, New Delhi, India

Given the alarming increase in obesity and associated NCDs, use of nutritional and medicinal plants in obesity management have come into focus. There is growing interest in pungent thermogenic plants with anti-obesity activity. With this in view, the study has explored the potential of NMR metabolomics to identify plants with anti-obesity activity based on their chemosensory and thermogenic properties, the latter evaluated by Differential Scanning Calorimeter. Multivariate analysis of NMR data discriminated thermogenic (pungent) and non-thermogenic (sweet) plants and also correlated well with the calorimetry analyses. NMR can identify quickly plants with anti-obesity potential using their chemosensory associated thermogenic properties.

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