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Abstract #2918

Determination of Metabolite T2-Relaxation in the Medial Prefrontal Cortex at 7T Using an 8Tx/8Rx Channel Head Coil

Ariane Fillmer1, Layla Tabea Riemann1, Frank Seifert1, Semiha Aydin1, Harald Pfeiffer1, and Bernd Ittermann1
1Physikalisch-Technische Bundesanstalt (PTB), Braunschweig und Berlin, Germany

To investigate underlying mechanisms of psychiatric diseases, such as schizophrenia, magnetic resonance spectroscopy is a powerful tool. Here, the medial prefrontal cortex is a region of high interest, however, high quality measurements are technically challenging, and proper absolute quantification is hindered by the lack of literature values for metabolite relaxation times. This work presents the acquisition of high-quality MR spectra from the medial prefrontal cortex, and the preliminary calculation of metabolite T2 relaxation times, using an 8Tx/8Rx channel coil with a dedicated phase set optimized for B1 efficiency in the frontal cortex.

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