Abstract #2940

In-vivo 1H-MRS Shows Differences in Polyunsaturated Fatty Acid Content between White and Brown Adipose Tissue in Humans.

Ronald Ouwerkerk¹, Jatin Raj Matta¹, Ahmed Hamimi¹, Aaron M Cypess², Kong Y Chen³, and Ahmed Medhat Gharib¹

¹Biomedical and Metabolic Imaging Branch, NIDDK/NIH, Bethesda, MD, United States, ²Translational Physiology Section, Diabetes, Endocrinology, and Obesity Branch, NIDDK/NIH, Bethesda, MD, United States, ³Energy Metabolism Section, Diabetes, Endocrinology, and Obesity Branch, NIDDK/NIH, Bethedsa, MD, United States

Localized 1H-MRS was used to compare the fatty acid composition and MR relaxation in PET proven metabolically active brown adipose tissue (BAT) in humans with white adipose tissue (WAT). Paired comparison of BAT and WAT results from the same individuals the showed differences in MR relaxation of fatty acid resonances and unsaturated fatty acid content between metabolically activatable brown fat and white adipose tissue

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