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Abstract #3004

Boosting the sensitivity of MRI: 10,000 Tesla equivalent water proton signal

Arthur C. Pinon1, Andrea Capozzi1, and Jan Henrik Ardenkjær-Larsen1
1Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

In recent years, hyperpolarization of water protons via dissolution Dynamic Nuclear Polarization has attracted increasing interest in the magnetic resonance community. Hyperpolarized water may provide an alternative to Gd-based contrast agents, and it may report on chemical and biochemical reactions, and proton exchange. However, hyperpolarizing water protons is challenging, since the presence of radicals is the main source of relaxation during dissolution and transfer to the MRI system. In this work, we report water signals otherwise requiring >10,000 T at room temperature by employing UV-generated labile radicals, opening up for novel MRI applications.

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