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Abstract #3047

Effective MR Molecular Imaging of Prostate Cancer with an EDB-Fibronectin-Specific Contrast Agent at Reduced Doses

Nadia Ayat1, Sarah Roelle1, Songqi Gao1, Yajuan Li1, and Zheng-Rong Lu1
1Case Western Reserve University, Cleveland, OH, United States

This research highlights the potential of a targeted contrast agent specific to the extra-domain B (EDB-FN) to be utilized in the diagnosis of prostate cancer at reduced dosages. EDB-FN specific MR contrast agent MT218 produced robust tumor enhancement at dosages as low as 0.02 mmol Gd/kg.

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