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Abstract #3055

Rigid Motion Correction for High Resolution Brain PET/MR Imaging

Mohammad Mehdi Khalighi1, Mackenzie Carlson2, Matthew Spangler-Bickell3, Timothy Deller4, Kristen Wangerin4, Dan Rettmann4, Tim Skloss4, Brian Burns4, Dawn Holley1, Kim Halbert1, Tyler N Toueg5, Phillip S DiGiacomo1, Murat Aksoy6, Julian Maclaren6, Roland Bammer6, Floris Jansen4, Fred T. Chin1, Michael Moseley1, Greg Zaharchuk1, Elizabeth Mormino5, and Michael Zeineh1
1Radiology, Stanford Univ., Stanford, CA, United States, 2Bioengineering, Stanford Univ., Stanford, CA, United States, 3Was with: Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy, 4GE Healthcare, Waukesha, WI, United States, 5Neurology, Stanford Univ., Stanford, CA, United States, 6HobbitView, San Jose, CA, United States

In a brain PET/MR scan, the PET acquisition is done during the entire exam which typically lasts between 30-60 min. Most subjects, especially patients with a motion disorder or AD, exhibit some degree of motion which results in image blurring, quantitative errors due to mismatched attenuation correction, and mis-registered PET and MR images which limits the advantages of PET reconstruction using anatomical priors. In this study, we describe the benefits of an optical motion tracking technique, which has been recently introduced for PET/MR, to acquire high resolution isotropic PET/MR images.

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