In a brain PET/MR scan, the PET acquisition is done during the entire exam which typically lasts between 30-60 min. Most subjects, especially patients with a motion disorder or AD, exhibit some degree of motion which results in image blurring, quantitative errors due to mismatched attenuation correction, and mis-registered PET and MR images which limits the advantages of PET reconstruction using anatomical priors. In this study, we describe the benefits of an optical motion tracking technique, which has been recently introduced for PET/MR, to acquire high resolution isotropic PET/MR images.
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