Abstract #3115

Dynamic glucose-enhanced (DGE) MRI for brain tumors: a small-scale clinical observational study

Jianhua Mo¹, Xiang Xu^2,3, Xianglong Wang¹, Linda Knutsson^2,4, Akansha A Sehgal^2,3, Peter C. M. van Zijl^2,3, and Zhibo Wen¹

¹Zhujiang Hospital, Southern Medical University, Guangzhou, China, ²Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, United States, ³F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, MD, United States, ⁴Department of Medical Radiation Physics, Lund University, Lund, Sweden

Dynamic glucose-enhanced (DGE) MRI has shown potential for imaging glucose delivery and blood brain barrier permeability. Previous reports focused on the technical development of DGE and only a few clinical brain tumor cases have been reported. Here we incorporated the current DGE protocol into our routine MRI examination at 3T and performed a small-scale clinical observational study on patients with different types of brain tumors. Despite the technical challenges of DGE at clinical scanners, we observed different (non)-enhancement patterns with various brain tumor types.

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