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Abstract #3122

Development of a standard phantom for Chemical Exchange Saturation Transfer MRI

Shu Zhang1, F. William Schuler1, Tianzhe Li1, Ken-Pin Hwang2, Mitsuharu Miyoshi3, Xinzeng Wang4, and Mark D. Pagel1
1Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, United States, 2Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States, 3Global MR Applications & Workflow, GE Healthcare Japan, Tokyo, Japan, 4Global MR Applications & Workflow, GE Healthcare, Houston, TX, United States

Many clinical CEST MRI methods have been developed and disseminated during the last few years, and the expansion of clinical CEST MRI will likely continue. A common phantom is needed to standardize the development and implementation of CEST methods. In this study, we have developed a clinical CEST MRI phantom with high-quality gelatin to test a range of concentrations, pH values, and T1 relaxation times. The experimental conditions of the CEST saturation and various post-saturation acquisition methods can be tested. This standard phantom can be used to support many applications within the CEST MRI research community.

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