Single point magnetization transfer (MT) is a quantitative method which reduces the number of unknowns in the MT signal equation by fixing tissue parameters which are effectively constant such that the macromolecular proton fraction (MPF) is the only remaining variable. In this work, the nonlinear signal equation describing single point MT was inverted to obtain an analytic expression for MPF as a function of observed normalized signal (MT∆/MT0). This enables rapid computation of MPF maps from matrix operations performed on the 3D images of the MT-weighted image (MT∆), the MT reference image, (MT0), and separately acquired T1 and B1 maps.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords