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Abstract #3149

Fat DESPOT for MR-oximetry validated by STEAM MRS

VĂ©ronique Fortier1,2 and Ives R. Levesque1,2,3
1Medical Physics Unit, McGill University, Montreal, QC, Canada, 2Biomedical Engineering, McGill University, Montreal, QC, Canada, 3Research Institute of the McGill University Health Centre, Montreal, QC, Canada

The R1 relaxation rate of fat is a promising biomarker for mapping tissue oxygenation. Existing techniques to map fat R1 are limited to single-voxel or 2D imaging with long scan times. To address these limitations, this work presents a 3D technique to map fat R1 using a fat-water-separated variable flip angle (VFA) approach. The sensitivity of this technique to oxygenation variations was evaluated in a phantom. The results showed that fat R1 can be measured using a technique based on 3D VFA at 3 T and is feasible for MR-oximetry.

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