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Abstract #3153

Relaxometry Differences Between Magno- and Parvocellular Human LGN Subdivisions Revealed by In- and Ex-vivo Quantitative MRI

Christa Müller-Axt1,2, Cornelius Eichner1, Louise Kauffmann1,3, Pierre-Louis Bazin1,4, Henriette Rusch5, Markus Morawski5, Alfred Anwander1, and Katharina von Kriegstein2
1Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, 2Faculty of Psychology, Technical University of Dresden, Dresden, Germany, 3LPNC, Grenoble Alpes University, Grenoble, France, 4Integrative Model-based Cognitive Neuroscience Research Unit, Department of Psychology, University of Amsterdam, Amsterdam, Netherlands, 5Paul Flechsig Institute of Brain Research, University of Leipzig, Leipzig, Germany

The human lateral geniculate nucleus (LGN) is the central station for visual processing before information reaches the cerebral cortex. It is characterized by subdivisions with distinct cyto- and myeloarchitecture. Due to its small size, imaging of the LGN and especially its subdivisions is challenging. Here, we show that the LGN and its subdivisions can be identified using in-vivo and ex-vivo high-field quantitative MRI with ultra-high resolution. We present the to-date first atlas of the LGN and its estimated subdivisions. This work will serve as a highly valuable tool both for neuroscientists and clinicians investigating the visual system and its disorders.

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