Abstract #3154

Quantitative Imaging Metrics Derived from MR Fingerprinting using ISMRM/NIST System Phantom: An International Multi-Center Test-Retest Study

Amaresha Konar Shridhar¹, Enlin Qian², Sairam Geethanath², Guido Buonincontri³, Maggie M Fung⁴, Nancy A Obuchowski⁵, Pedro Gomez⁶, Rolf Schulte⁷, Lawrence H Schwartz⁸, and Amita Shukla-Dave^1,9

¹Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States, ²Columbia Magnetic Resonance Research Center, Columbia University, New York, NY, United States, ³Imago7 Foundation, Pisa, Italy, ⁴MR Apps & Workflow, GE Healthcare, New York, NY, United States, ⁵Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, United States, ⁶Global Research, GE Healthcare, Munich, Germany, ⁷MR Workflow & Application Team, GE Healthcare, New York, NY, United States, ⁸Department of Radiology, Columbia University Medical Center, New York, NY, United States, ⁹Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States

The present study performed the repeatability and reproducibility test for T₁, and T₂ values estimated using MR fingerprinting (MRF) method. MRF data have been acquired over 30 days at three different centers (center-1 (USA): 1.5T and 3T, center-2 (USA): 3T and center-3 (Italy): 1.5T) using ISMRM/NIST MRI system phantom. MRF based estimated T₁ and T₂ values are compared with the vendor provided values and standard inversion recovery spin echo and a multiple single-echo spin-echo method as scanner Ground Truth (GT) values. The results show that the T₁ and T₂ values estimated using the MRF method are highly repeatable and reproducible.

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