T1 quantification is a valuable biomarker for liver function estimation and fibrosis staging. The presence of fat would confound the measurement of tissue T1. Chemical shift encoded fat-water separation combined variable flip angle (CSE-VFA) T1 mapping could remove the bias from fat signals, but B1 inhomogeneity would be a serious problem in abdominal applications. In this work, we proposed to combine the DREAM sequence with CSE-VFA, so that PDFF/T1/B1/R*2 could be simultaneously estimated. The deviation of the T1 values between the results with and without B1 correction verified the necessity of B1 measurements in the abdominal application.
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