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Abstract #3161

Multi-compartment T1 relaxometry with inversion recovery sequence: a fat-water phantom study

Hao Peng1, Liwen Wan1, Qian Wan1, Chuanli Cheng1, Xin Liu1, Hairong Zheng1, and Chao Zou1
1Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences, Shenzhen, China

T1 relaxation time has been a valuable biomarker with emerging applications in cardiac diseases and liver function. Traditional inversion-recovery T1 quantification method is frequently applied as the reference for various T1 quantification methods. When applied in targets where fat and water signals co-exists, the single component fitting model would be in a dilemma. Combining the inversion-recovery T1 quantification with existing fat-water quantification methods, this work presented a solution for multi-component T1 quantification. Proposed method has been tested on fat-water phantoms and showed good consistency over a wide range of fat fractions.

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