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Abstract #3165

A stability study of breath-hold and free-breathing liver fat and R2* quantification at 1.5T and 3T

Chang Gao1,2,3, Peng Hu1,2, Brian Dale4, Marcel D. Nickel5, Stephan A.R. Kannengiesser5, Berthold Kiefer5, Vibhas Deshpande6, and Xiaodong Zhong3
1Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, United States, 2Physics and Biology in Medicine Inter-departmental Graduate Program, David Geffen School of Medicine, University of California, Los Angeles, CA, United States, 3MR R&D Collaborations, Siemens Healthcare, Los Angeles, CA, United States, 4MR Training, Siemens Healthcare, Cary, NC, United States, 5MR Application Development, Siemens Healthcare GmbH, Erlangen, Germany, 6MR R&D Collaborations, Siemens Healthcare, Austin, TX, United States

Accurate quantification of proton-density fat fraction (PDFF) and R2* requires appropriate compensation of various confounding factors. A stability study was performed to investigate the impacts of different protocols and imaging parameters using both breath-hold Cartesian and free breathing radial sequences on a standardized phantom and a group of 5 same normal subjects at both 1.5T and 3T. This study revealed that flip angle, TE mode and coil usage were important protocol parameters to investigate further in larger patient population.

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