Abstract #3165

A stability study of breath-hold and free-breathing liver fat and R2* quantification at 1.5T and 3T

Chang Gao^1,2,3, Peng Hu^1,2, Brian Dale⁴, Marcel D. Nickel⁵, Stephan A.R. Kannengiesser⁵, Berthold Kiefer⁵, Vibhas Deshpande⁶, and Xiaodong Zhong³

¹Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, United States, ²Physics and Biology in Medicine Inter-departmental Graduate Program, David Geffen School of Medicine, University of California, Los Angeles, CA, United States, ³MR R&D Collaborations, Siemens Healthcare, Los Angeles, CA, United States, ⁴MR Training, Siemens Healthcare, Cary, NC, United States, ⁵MR Application Development, Siemens Healthcare GmbH, Erlangen, Germany, ⁶MR R&D Collaborations, Siemens Healthcare, Austin, TX, United States

Accurate quantification of proton-density fat fraction (PDFF) and R2* requires appropriate compensation of various confounding factors. A stability study was performed to investigate the impacts of different protocols and imaging parameters using both breath-hold Cartesian and free breathing radial sequences on a standardized phantom and a group of 5 same normal subjects at both 1.5T and 3T. This study revealed that flip angle, TE mode and coil usage were important protocol parameters to investigate further in larger patient population.

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