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Abstract #3177

MR signal modelling comparison and its influence on tissue parameters using gradient-echo MRI at 7 Telsa

KIRAN THAPALIYA1,2, Viktor Vegh2, Steffen Bollmann2, and Markus Barth2,3
1Menzies Health Institute Queensland, Griffith University, Gold coast, Australia, 2Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia, 3School of Information Technology and Electrical Engineering, The University of Queensland, Brisbane, Australia

Quantitative assessment of model parameters (water fraction and frequency shift) estimated using a multi-compartment model can be useful to study tissue properties in white matter. In this work, we compared common existing complex signal models for multi-echo gradient echo data acquired at 3T and 7T. We investigate the variation of model parameters that could potentially affect different models (number of compartments and parameters) on the estimation of tissue parameters. We show that the tissue parameters vary across the sub-regions of the corpus callosum and are influenced by different modelling choices.

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