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Abstract #3179

Current Density Measurements in the Human Brain in-vivo during TES treatment, using Multi-Band methods

Munish Chauhan1, Sulagna Sahu1, Saurav Zaman Khan Sajib1, Enock Boakye1, Michael Schär2, and Rosalind J Sadleir1
1School of Biological and Health System Engineering, Arizona State University, Tempe, AZ, United States, 2Department of Radiology, Johns Hopkins University, Baltimore, MD, United States

Current density distribution measured in the brain can guide and verify electrical stimulation therapies. Recent studies have demonstrated current density images of human heads during TES using Magnetic Resonance Electrical Impedance Tomography (MREIT). Earlier MREIT approaches permitted imaging of three 5-mm-thick slices in a sequence lasting 6 minutes, a typical therapeutic TES administration time. MREIT sequences must be accelerated to obtain whole brain coverage. In this study, we demonstrate in-vivo use of multiband-accelerated multi-echo-gradient-echo MREIT acquisition methods to acquire 24 5-mm-thick slices over 6 minutes. Computed current density maps measured in the brain using both methods are compared.

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