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Abstract #3212

Sampling and Modeling UTE Signals is Important to Estimate Bone Marrow Susceptibility

Christof Böhm1, Sophia Kronthaler1, Maximilian N. Diefenbach1,2, Jakob Meineke3, and Dimitrios C. Karampinos1
1TUM, Munich, Germany, 2Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU, Division, Munich, Germany, 3Philips Research, Hamburg, Germany

Body QSM relies on accurate magnetic field-mapping. A well-established water–fat voxel signal model with shared $$$R_2^*$$$ has successfully been used for body QSM based on multi-echo data at conventional echo times. However, when UTE echoes are recorded to obtain field-map information in previously unavailable MR signal voids, such as trabecular bone, the above water–fat model is no longer accurate. Therefore a joint 2-signal-model fitting using graph-cuts is proposed and applied. Further, this work demonstrates the importance of UTE echoes to obtain correct susceptibility values of cortical bone and more importantly, for bone marrow.

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