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Abstract #3214

Sensitivity of Quantitative Susceptibility Mapping to Temperature: A Phantom Study

Hirohito Kan1,2, Yuto Uchida3,4, Masahiro Takizawa5, Tosiaki Miyati6, Hiroshi Kunitomo7, Nobuyuki Arai7, Harumasa Kasai7, and Yuta Shibamoto2
1Radiological and Medical Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya City, Japan, 2Department of Radiology, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Japan, 3Department of Neurology, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Japan, 4Department of Neurology, Toyokawa City Hospital, Toyokawa, Japan, 5Healthcare Business Unit, Hitachi, Ltd., Tokyo, Japan, 6Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan, 7Department of Radiology, Nagoya City University Hospital, Nagoya City, Japan

To date, we are unaware of any reports regarding quantitative susceptibility mapping (QSM) at different temperatures. To clarify the temperature dependence of susceptibility estimated by QSM analysis, we investigated the relationships between temperature and susceptibility using a simple cylinder phantom with varying temperatures. This study has demonstrated that a significant inverse correlation was found between the temperature and the susceptibility value estimated by QSM analysis. This dependence might be the confounding factor of QSM-based iron estimation.

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