Abstract #3214

Sensitivity of Quantitative Susceptibility Mapping to Temperature: A Phantom Study

Hirohito Kan^1,2, Yuto Uchida^3,4, Masahiro Takizawa⁵, Tosiaki Miyati⁶, Hiroshi Kunitomo⁷, Nobuyuki Arai⁷, Harumasa Kasai⁷, and Yuta Shibamoto²

¹Radiological and Medical Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya City, Japan, ²Department of Radiology, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Japan, ³Department of Neurology, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Japan, ⁴Department of Neurology, Toyokawa City Hospital, Toyokawa, Japan, ⁵Healthcare Business Unit, Hitachi, Ltd., Tokyo, Japan, ⁶Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan, ⁷Department of Radiology, Nagoya City University Hospital, Nagoya City, Japan

To date, we are unaware of any reports regarding quantitative susceptibility mapping (QSM) at different temperatures. To clarify the temperature dependence of susceptibility estimated by QSM analysis, we investigated the relationships between temperature and susceptibility using a simple cylinder phantom with varying temperatures. This study has demonstrated that a significant inverse correlation was found between the temperature and the susceptibility value estimated by QSM analysis. This dependence might be the confounding factor of QSM-based iron estimation.

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