Meeting Banner
Abstract #3249

On the Saturation Scheme in Chemical Exchange Saturation Transfer Imaging with B0 Inhomogeneity

Ruibin Liu1, Qiuping Ding1, Yi-Cheng Hsu2, Yi Sun2, Dan Wu1, and Yi Zhang1
1Key Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, Zhejiang, China, 2MR Collaboration, Siemens Healthcare Ltd., Shanghai, China

Saturation pulses are an indispensable part in Chemical Exchange Saturation Transfer (CEST) imaging. Different saturation schemes can be designed for CEST imaging, including the pulse shape, duration of each pulse element, number of pulse elements, inter-pulse spoiler gradient, and inter-pulse gap, etc. Here, the impact of saturation schemes subject to practical B0 inhomogeneity is investigated, using Bloch simulations, and phantom and human experiments. Specifically, it’s shown that Gaussian and rectangular saturation pulses demonstrate substantially different susceptibility to imaging artifacts in the presence of B0 inhomogeneity when changing the duration of each saturation pulse element, and the inter-pulse spoiler gradients.

This abstract and the presentation materials are available to 2020 meeting attendees and eLibrary customers only; a login is required.

Join Here