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Abstract #3289

Optimizing an Array-Compressed Coil for Arterial Spin Labeling at 7T

Xinqiang Yan1,2, Manus J. Donahue1,2, and William A. Grissom1,2,3
1Department of Radiology, Vanderbilt University Medical Center, Nashville, TN, United States, 2Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States, 3Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States

Arterial spin labeling (ASL) is a primary approach for non-invasive perfusion measurements with MRI. Theoretically, performing ASL at ultrahigh magnetic field strength can be beneficial because of the increased SNR as well as the lengthened T1-relaxation time. However, ASL is still not widely used at 7T due to the obstacles of B1+ inhomogeneity and high SAR associated with labeling. To overcome this problem, we apply array compressed parallel transmission (acpTx) in ASL and find that the optimized coil achieved 2x better B1+ homogeneity, and 4x lower SAR than a conventional 8-channel coil, which could enable 7T ASL with neck labeling.

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