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Abstract #3313

Comparison of multi-platform 2D and 3D MR elastography in vivo and in vitro

Paul Kennedy1,2, Daniel Stocker1,2, Octavia Bane1,2, Stefanie Hectors1,2,3, Bradley D Bolster Jr. 4, and Bachir Taouli1,2
1BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 2Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 3Department of Radiology, Weill Cornell Medicine, New York, NY, United States, 4Siemens Medical Solutions USA, Inc., Salt Lake City, UT, United States

In this study we assess the variation in 2D and 3D MR elastography (MRE) measures in patients, volunteers and a phantom across two MR system vendors. Interobserver variability was also examined. 2D and 3D MRE liver measurements were not significantly different across systems and showed excellent intraclass correlation coefficient (ICC) between readers. Spleen measurement showed excellent ICC between readers but significant variation in 3D MRE spleen stiffness was found between systems. Liver 3D MRE is stable across platforms however further study is required to assess the bias in 3D MRE spleen measurements from multiple vendors.

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