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Abstract #3334

Validation of the Accuracy of Magnetic Resonance Elastography of the Liver via 3D Finite Element Modelling Simulation

Deirdre McGrath1,2, Christopher Bradley1,2, and Susan Francis1,2
1NIHR Nottingham Biomedical Research Centre, Radiological Sciences, Division of Clinical Neuroscience, Queens Medical Centre, Nottingham, United Kingdom, 2Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom

In this novel study, magnetic resonance elastography (MRE) of the liver is simulated in a detailed 3D anthropomorphic finite element model of the human torso, to explore the influence of imaging spatial resolution and motion-based signal to noise ratio (SNR) on the accuracy of elastograms calculated by direct inversion. It was found that MRE accuracy was highly dependent on imaging voxel dimensions, motion-SNR and the ground truth material properties. These findings will guide the optimisation and development of future liver MRE methodology.

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