Abstract #3349

Quantitative Assessment MR-Assisted PET Respiratory Motion Correction in Colorectal Liver Metastases using PET/MR

Sihao Chen^1,2, Cihat Eldeniz², Yasheng Chen³, and Hongyu An²

¹Biomedical Engineering, Washington University in St. Louis, Saint Louis, MO, United States, ²Mallinckrodt Institute of Radiology, Washington University in St. Louis, Saint Louis, MO, United States, ³Department of Neurology, Washington University in St. Louis, Saint Louis, MO, United States

Respiratory motion causes signal blurring and reduced tumor-to-background ratio (TBR). Simultaneous PET/MR imaging uniquely allows for MR-assisted motion correction in PET imaging, potentially leading to improved PET images for detection of lesions. In this study, we implemented several MR-assisted PET motion correction methods, including gated reconstruction (gated MoCo), reconstruct-transform-average (RTA) and motion-compensated image reconstruction (MCIR), to FDG imaging of colorectal liver metastases. We quantitatively compared TBR and CNR in FDG avid liver lesions. Our results demonstrated improvement of TBR and CNR using MCIR.

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