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Abstract #3349

Quantitative Assessment MR-Assisted PET Respiratory Motion Correction in Colorectal Liver Metastases using PET/MR

Sihao Chen1,2, Cihat Eldeniz2, Yasheng Chen3, and Hongyu An2
1Biomedical Engineering, Washington University in St. Louis, Saint Louis, MO, United States, 2Mallinckrodt Institute of Radiology, Washington University in St. Louis, Saint Louis, MO, United States, 3Department of Neurology, Washington University in St. Louis, Saint Louis, MO, United States

Respiratory motion causes signal blurring and reduced tumor-to-background ratio (TBR). Simultaneous PET/MR imaging uniquely allows for MR-assisted motion correction in PET imaging, potentially leading to improved PET images for detection of lesions. In this study, we implemented several MR-assisted PET motion correction methods, including gated reconstruction (gated MoCo), reconstruct-transform-average (RTA) and motion-compensated image reconstruction (MCIR), to FDG imaging of colorectal liver metastases. We quantitatively compared TBR and CNR in FDG avid liver lesions. Our results demonstrated improvement of TBR and CNR using MCIR.

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