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Abstract #3444

Phase Reconstruction using Iterative Multi-shot ESPIRiT (PRIME)

Stephen Cauley1,2, Bryan Clifford3, Steffen Bollmann3, Thorsten Feiweier4, Berkin Bilgic1,2, Kawin Setsompop1,2,5, and Lawrence L. Wald1,2,5
1Department of Radiology, A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 2Harvard Medical School, Boston, MA, United States, 3Siemens Medical Solutions USA, Boston, MA, United States, 4Siemens Healthcare GmbH, Erlangen, Germany, 5Harvard-MIT Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States

We employ a compact phase modeling strategy for accurate multi-shot echo-planar imaging (msEPI) reconstruction. As an alternative to approaches that perform msEPI reconstruction using strict low-rank constraints, we recast the problem as an iterative relative phase estimation problem. This allows for us to utilize existing techniques such as ESPIRiT, which are formulated for determining relative magnitude and phase differences between multi-coil receive arrays. Through an iterative search we jointly estimate an artifact-free combined image and the smooth relative phase between each msEPI shot. We demonstrate the benefits of our approach for clinical and highly-accelerated multi-shot diffusion-weighted acquisitions.

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