We present a phase unwrapping algorithm (ROMEO), which improves on previous path-based unwrapping methods by using weights (the values of which determine the order in which voxels are unwrapped) that guide the unwrapping on paths through the object which avoid noise and a computationally efficient minimum spanning tree algorithm. ROMEO was tested against the region-growing method PRELUDE and the voxel-based method Best Path in unwrapping simulated data (a complex topography) and in-vivo GRE and EPI data acquired at 7T. ROMEO was found to be faster and more reliable than PRELUDE and Best Path.
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