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Abstract #3706

High resolution multi T1-weighted contrast with reduced B1 sensitivity using the FLAWS sequence at 7T

Jeremy Beaumont1,2, Giulio Gambarota1, Herve Saint-Jalmes1, Oscar Acosta1, Jean-Christophe Ferré3,4, Parnesh Raniga2, Olivier Salvado5, and Jurgen Fripp2
1Univ Rennes, CRLCC Eugene Marquis, Inserm, LTSI-UMR 1099, F-35000 Rennes, France, 2The Australian e-Health Research Centre, CSIRO, Brisbane, Australia, 3Univ Rennes, Inria, CNRS, Inserm, IRISA, EMPENN ERL U-1228, F-35000 Rennes, France, 4CHU Rennes, Department of Neuroradiology, F35033 Rennes, France, 5Data 61, CSIRO, Brisbane, Australia

Recent studies showed that the FLAWS sequence provides multiple co-registered T1-weighted contrasts of the brain that exhibit reduced B1 sensitivity. In particular, the FLAWS sequence allows for the generation of a standard anatomical contrast, a contrast with WM signal suppression and a GM-specific contrast. This study introduces a combination of FLAWS images to generate a new contrast that may be suitable for the detection of brain lesions at 7T. While the preliminary results of this study are promising, a further validation is required by imaging subjects with lesions and comparing the new FLAWS contrast with other MR sequences.

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