Abstract #3707

High resolution T1 mapping with reduced B1+ sensitivity using the FLAWS sequence at 7T

Jeremy Beaumont^1,2, Giulio Gambarota¹, Herve Saint-Jalmes¹, Oscar Acosta¹, Parnesh Raniga², Olivier Salvado³, and Jurgen Fripp²

¹Univ Rennes, CRLCC Eugene Marquis, Inserm, LTSI-UMR 1099, F-35000 Rennes, France, ²The Australian e-Health Research Centre, CSIRO, Brisbane, Australia, ³Data 61, CSIRO, Brisbane, Australia

The MP2RAGE sequence can be used to provide 7T T1-weighted images and T1 maps with reduced transmitted bias field (B1⁺) sensitivity, at the cost of limiting the image resolution and contrast to noise ratio (CNR). The FLAWS sequence was derived from the MP2RAGE sequence to provide multiple T1-weigthed contrasts that were shown to be of interest for a wide range of clinical applications. The current study shows that the FLAWS sequence can be used to generate 7T T1-weigthed images and T1 maps with reduced B1⁺ sensitivity, while overcoming the resolution and CNR limitations imposed to the MP2RAGE sequence.

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