Abstract #3756

Quantitative Tracking of T1 and T2* in DCE-MRI by Dynamic MR Fingerprinting

Xueying Zhao¹, Ying-Hua Chu², Qianfeng Wang¹, and He Wang^1,3

¹Institute of Science and Technology for Brain-inspired Intelligence, Fudan University, Shanghai, China, ²MR Collaboration, Siemens Healthcare Ltd., Shanghai, China, ³Human Phenome Institute, Fudan University, Shanghai, China

Precise quantification of the contrast agent uptake in DCE-MRI is still challenging. Here, we redesigned the reconstruction scheme of MR fingerprinting by introducing a sliding window into the process of dictionary matching, which allows dynamic quantification of T1 and T2* in DCE-MRI with high temporal resolution. The performance of this proposed dynamic MRF method is simulated and tested on MATLAB. The time-varying trajectories of T1 and T2* have been successfully captured with a temporal resolution of 4.5 seconds. This method may open the door of utilizing MR fingerprinting to quantify time-varying variable with adjustable temporal resolution.

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