Contrast-enhanced breast MRI is the most sensitive tool for the detection of breast cancer. Contrast enhancement is however not specific to cancer: incidental benign findings regularly require further workup including ultimately avoidable follow-up scans and biopsies. Quantitative T1 and T2 measurements could be used as discriminative imaging markers to assist clinical decision-making. This feasibility study illustrates the potential clinical benefits of quantitative imaging for breast MRI by combining two fast and robust mapping techniques for high-resolution parameter mapping in a clinically feasible scan time of 7:32 min using prototype compressed sensing MP2RAGE and GRAPPATINI sequences with a harmonized protocol.
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