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Abstract #3769

Quantitative and Synthetic MRI for Breast Assessment in Clinical Acquisition Times

Nina Pötsch1, Marcus Raudner1,2, Tom Hilbert3,4,5, Tobias Kober3,4,5, Elisabeth Weiland6, Panagiotis Kapetas1, and Pascal Baltzer1
1Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 2High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 3Advanced Clinical Imaging Technology, Siemens Healthcare, Lausanne, Switzerland, 4Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 5LTS5, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 6Siemens Healthcare GmbH, Erlangen, Germany

Contrast-enhanced breast MRI is the most sensitive tool for the detection of breast cancer. Contrast enhancement is however not specific to cancer: incidental benign findings regularly require further workup including ultimately avoidable follow-up scans and biopsies. Quantitative T1 and T2 measurements could be used as discriminative imaging markers to assist clinical decision-making. This feasibility study illustrates the potential clinical benefits of quantitative imaging for breast MRI by combining two fast and robust mapping techniques for high-resolution parameter mapping in a clinically feasible scan time of 7:32 min using prototype compressed sensing MP2RAGE and GRAPPATINI sequences with a harmonized protocol.

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