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Abstract #3773

CRISTINA: Cartesian Single and Triple Quantum Imaging of 23Na in the Brain  

Michaela A U Hoesl1, Lothar R Schad1, and Stanislas Rapacchi2
1Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, 2Aix-Marseille University, CRMBM, CNRS, Marseille, France

Multi-quantum sodium imaging offers additional insights compared to standard single-quantum (SQ) images with information beyond tissue sodium concentration (TSC). Simulation including B0 inhomogeneity and stimulated echo signals of multi-quantum signals and spectra of phase cycle choices facilitated robust sequence development. The characteristic temporal evolution of the SQ and triple quantum (TQ) sodium is of interest and a multi echo sequence for SQ and TQ signal acquisition was developed, which was evaluated in phantom and 5 healthy volunteers in the brain.

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