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Abstract #3774

Phantom study on magnetic resonance imaging (MRI) T1 and T2 relaxation times measurements standardization

Davide Cicolari1, Domenico Lizio2, Patrizia Pedrotti3, Monica Teresa Moioli2, Alessandro Lascialfari1, Manuel Mariani1, and Alberto Torresin2,4
1Department of Physics, Università degli Studi di Pavia, Pavia, Italy, 2Department of Medical Physics, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, 3Department of Cardiology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, 4Department of Physics, Università degli Studi di Milano, Milan, Italy

Relaxation times measurement standardization, a great issue in clinical inter-centre and inter-scanner applications, is studied by comparing relaxation times maps of a MnCl2 phantom, scanned with two different MRI imagers, with reference values measured with an NMR laboratory spectrometer. For this study standard sequences were used: NMR reference T1 and T2 values were obtained from IR (Inversion-Recovery) and CPMG (Carr-Purcell-Meiboom-Gill) sequences respectively; MRI maps were generated from clinical IR and SE (Spin-Echo) sequences. The MRI and NMR results agreement within the experimental error limits (5%) suggests that the estimation of the relaxation times is independent from the spectrometer/scanner utilized.

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