Abstract #3774

Phantom study on magnetic resonance imaging (MRI) T1 and T2 relaxation times measurements standardization

Davide Cicolari¹, Domenico Lizio², Patrizia Pedrotti³, Monica Teresa Moioli², Alessandro Lascialfari¹, Manuel Mariani¹, and Alberto Torresin^2,4

¹Department of Physics, Università degli Studi di Pavia, Pavia, Italy, ²Department of Medical Physics, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, ³Department of Cardiology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, ⁴Department of Physics, Università degli Studi di Milano, Milan, Italy

Relaxation times measurement standardization, a great issue in clinical inter-centre and inter-scanner applications, is studied by comparing relaxation times maps of a MnCl₂ phantom, scanned with two different MRI imagers, with reference values measured with an NMR laboratory spectrometer. For this study standard sequences were used: NMR reference T₁ and T₂ values were obtained from IR (Inversion-Recovery) and CPMG (Carr-Purcell-Meiboom-Gill) sequences respectively; MRI maps were generated from clinical IR and SE (Spin-Echo) sequences. The MRI and NMR results agreement within the experimental error limits (5%) suggests that the estimation of the relaxation times is independent from the spectrometer/scanner utilized.

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