We proposed a modified T2-based water suppression synthetic-MRI technique without loss of tissue SNR, which was introduced by subtraction of heavy-T2W image from standard acquired images. Our water suppression was achieved by subtracting only water portions except for tissue portions. We demonstrated both effects that CSF-PVE artifacts were dramatically suppressed and the tissue SNR was kept to before subtraction in our water suppressed quantitative maps; and thus water suppressed synthetic images of FLAIR and SE provided better gray-white matter contrasts than those for subtracting uniformly.
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