Abstract #3780

T1ρ could be a complementary tool for T2* in the assessment of rat liver iron overload

Qianfeng Wang¹, Hong Xiao², He Wang¹, Xuchen Yu¹, and Fuhua Yan²

¹Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, ²Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

In this study, spin-lock and 2D UTE pulse sequences were developed to quantify T_1ρ and T₂* of 32 rat livers with iron overload at 11.7T MR system. Moreover, T₂ was also acquired to compare with T_1ρ and T₂*. Pearson correlation analyses (two-tailed) illustrated that T_1ρ were significantly associated with T₂ (all p ≤ 0.002), but insignificantly related with T₂* (all p > 0.05). No significant association was found between T₂ and T₂*.

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