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Abstract #3780

T1ρ could be a complementary tool for T2* in the assessment of rat liver iron overload

Qianfeng Wang1, Hong Xiao2, He Wang1, Xuchen Yu1, and Fuhua Yan2
1Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, 2Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

In this study, spin-lock and 2D UTE pulse sequences were developed to quantify T and T2* of 32 rat livers with iron overload at 11.7T MR system. Moreover, T2 was also acquired to compare with T and T2*. Pearson correlation analyses (two-tailed) illustrated that T were significantly associated with T2 (all p ≤ 0.002), but insignificantly related with T2* (all p > 0.05). No significant association was found between T2 and T2*.

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