Abstract #3785

Fast, high resolution QSM of the brainstem at 7T using super-resolution 2D EPI

Andreas Ehrmann¹, Beata Bachrata^1,2, Korbinian Eckstein¹, David Bancelin¹, Pedro Lima Cardoso¹, Charles Joseph Guthrie¹, Siegfried Trattnig^1,2, and Simon Daniel Robinson^1,3,4

¹High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ²Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, ³Department of Neurology, Medical University of Graz, Graz, Austria, ⁴Centre for Advanced Imaging, University of Queensland, Queensland, Australia

2D EPI-based Quantitative Susceptibility Mapping offers a means to localise brainstem structures very quickly. However, this comes at the price of limited achievable slice thickness, restricting the precision of the localisation. In this work, we develop a fast super-resolution reconstruction method for complex MRI data, allowing the reconstruction of high resolution magnitude and phase images, and hence also high resolution susceptibility maps. We demonstrate that the reconstructed super-resolution 2D EPI images significantly improve the visibility of small structures allowing for improved localisation of the brainstem and other small structures such as veins in the generated susceptibility maps.

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