Meeting Banner
Abstract #3800

Quantitative Macromolecular Proton Fraction Imaging Based On Spin-Lock

Jian Hou1, Vincent Wong2, Baiyan Jiang1, Yixiang Wang1, Anthony Chan3, Winnie Chu1, and Weitian Chen1
1Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Hong Kong, Hong Kong, 2Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong, 3Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong, Hong Kong

Macromolecular Proton Fraction (MPF) is the relative amount of protons associated with macromolecules involved in magnetization transfer with free water protons. MPF is typically measured by quantitative magnetization transfer methods. In this work, we reported that MPF can also be measured based on spin-lock. Compared to the existing MPF methods, our method requires fewer parameter maps. We demonstrated our method using simulation, phantom, and in vivo experiments.

This abstract and the presentation materials are available to 2020 meeting attendees and eLibrary customers only; a login is required.

Join Here