Macromolecular
Proton Fraction (MPF) is the relative amount of protons associated with
macromolecules involved in magnetization transfer
with free water protons. MPF is typically measured by quantitative
magnetization transfer methods. In this work, we reported that MPF can also be
measured based
on spin-lock. Compared
to the existing MPF methods, our method requires fewer parameter maps.
We demonstrated our method using simulation, phantom, and in
vivo experiments.
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