Idiopathic Pulmonary Fibrosis (IPF) is a palliative lung condition. Neuroimaging has the potential to shed light on the neural pathways of cough, a common, troublesome symptom in IPF. However, given the nature of the condition, it is important to first understand the physiological state of brain tissue before investigating functional networks. No significant differences in brain volume were observed in IPF patients but a localised reduction in resting perfusion was seen. There was no difference in functional response when performing a combined motor and visual task. The results support future neuroimaging investigation into the cough pathway in IPF.
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