Fast-fMRI has become a potent tool in researching brain physiology more accurately than before and it can detect changes in the blood oxygen level‐dependent signal, even if there is no epileptiform activity present. These detectable changes suggest that in epilepsy there are alterations in the brain physiology. With utilization of coefficient of variation (CV) method for patients with epilepsy (PWE), we detected a robust increase of CV in patients with in white matter, brainstem and temporal lobes in PWE at group level. Importantly, individual mapping of possible epileptic abnormality is also possible.
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