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Abstract #3835

Respiratory related brain pulsations are disturbed in epilepsy

Janne Kananen1, Timo Tuovinen2, Vesa Korhonen2, Niko Huotari2, Hanna Ansakorpi3, Pierre LeVan4, and Vesa Kiviniemi2
1Medicine, Radiology, OFNI, University of Oulu, Oulu, Finland, 2University of Oulu, Oulu, Finland, 3Oulu University Hospital, Oulu, Finland, 4University of Freiburg, Freiburg, Germany

Fast-fMRI has become a potent tool in researching brain physiology more accurately than before and it can detect changes in the blood oxygen level‚Äźdependent signal, even if there is no epileptiform activity present. These detectable changes suggest that in epilepsy there are alterations in the brain physiology. With utilization of coefficient of variation (CV) method for patients with epilepsy (PWE), we detected a robust increase of CV in patients with in white matter, brainstem and temporal lobes in PWE at group level. Importantly, individual mapping of possible epileptic abnormality is also possible.

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