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Abstract #3891

Connectivity analyses of accelerated 3D resting-state ASL

Fanny Munsch1, Manuel Taso1, John A. Detre2, and David C. Alsop1
1Radiology, Division of MRI Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States, 2Neurology and Radiology, University of Pennsylvania, Philadelphia, PA, United States

We used a single-shot accelerated volumetric Arterial Spin Labeling (ASL) sequence to study brain connectivity in regions where resting-state (rs) BOLD analyses can be challenging due to low signal to noise ratio (SNR). Thus, we chose to study the medial prefrontal cortex, part of the default-mode network (DMN), and the subcallosal cortex for which RS-BOLD is impacted by susceptibility artifacts. We also studied the connectivity of the intracalcarine cortex because it belongs to a network involving deep nuclei, for which BOLD signal is reduced due to low blood volume.

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